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Those who knew him remember a unique combination of tolerance, firmness, kindness, and good sense with enduring humor. At Harvard he created the first department of neurobiology, in which he brought together people from different disciplines who developed new ways of thinking. Stephen Kuffler’s work exemplified and introduced a multidisciplinary approach to the study of the nervous system. Moreover, he himself had done every experiment he described. What gave papers by Stephen Kuffler a special quality were the clarity, the beautiful figures, and the underlying excitement. Examples are his studies on denervation, stretch receptors, efferent control, inhibition, GABA and peptides as transmitters, integration in the retina, glial cells, and the analysis of synaptic transmission. A feature of his work is the way in which the right problem was tackled using the right preparation. In a career that spanned 40 years, Stephen Kuffler made experiments on fundamental problems and laid paths for future research to follow. This book is dedicated to the memory of our friend and colleague, Steve Kuffler. Includes bibliographical references and index. FAX: 41 E-mail: Internet: Library of Congress Cataloging-in-Publication Data From neuron to brain / John G. 23 Plumtree Road Sunderland, MA 01375 U.S.A. Address inquiries and orders to Sinauer Associates, Inc.

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From Neuron to Brain, Fifth Edition Copyright © 2012 by Sinauer Associates, Inc. Neurons (background) are from the Third Edition cover, designed by Laszlo Meszoly. USA ABOUT THE COVER Computer artwork of a human brain © Pasieka/Science Photo Library/Fotosearch.Weisblat University of California, Berkeley Sinauer Associates, Inc. Diamond International School for Advanced Studies, Trieste, Italy David A. Brown University College London Mathew E.

Fuchs The Johns Hopkins University School of Medicine David A. Robert Martin Emeritus, University of Colorado School of Medicine Paul A. Nicholls International School for Advanced Studies, Trieste, Italy A. From Neuron to Brain FIFTH EDITION From Neuron to Brain FIFTH EDITION John G.

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